周乃玉教授“妙用柴胡剂,调畅气机巧治痹”

周乃玉主任医师,从事中医风湿病治疗40余载,经验丰富,方法独到,疗效卓著。她通过精研《黄帝内经》、《伤寒论》等古代经典文献,结合自己多年临床经验,创造性地将柴胡剂用于痹证治疗,开创了调畅少阳气机治痹的新方法。     

以《素问·移精变气论》为中心探讨上古时期的医学特点

文章围绕《素问·移精变气论》内容讨论上古时期医学的一些特点,旨在说明以内省为特点的中国传统文化特质对早期中医学的深远影响。同时,文章还探讨了内省文化中的定与慧在《黄帝内经》当中的体现。     

A factor analysis of the rat''s corpus callosum

Previous work from our laboratory (Berrebi et al., Brain Research, 438 (1988) 216-224) demonstrated region-specific sexual dimorphisms in the size of the rat's corpus callosum, which are modifiable by extra stimulation in early life. These differences are assumed to reflect regional corticocortical fibers of passage which are altered differentially by gender and our experimental manipulations. In this paper, we report our findings when the original data are reanalyzed using a newly developed computer program. This program not only reproduced, with very high accuracy, the original means, but also permitted us to examine computer generated callosal width scores via a factor analysis procedure. Such a procedure yields useful information concerning the clustering of callosal fibers and thus contributes significantly to our hypothesis that discrete cortical regions are selectively sensitive to experimental variables. Factor analyses of the callosal variables and brain weight of 155 rats found 7 width factors, and an eighth factor which contained the variables of brain weight, callosal length, and callosal perimeter. Callosal area did not load significantly on any of these factors. The percentile locations of the width factors, starting at the anterior (genu) end were: widths 1-5, 6-17, 24-38, 46-57, 62-72, 79-95 and 96-99. Use of these factor scores in analyses of variance revealed that the male callosum is wider than the female's, with the differences most pronounced in the genu and the most posterior portion of the splenium. Both age and early handling experience influenced the callosal width factors.(ABSTRACT TRUNCATED AT 250 WORDS)     

Glycogen phosphorylase activity in the olfactory bulb of the young rat

The activity of glycogen phosphorylase, the enzyme that controls glycogen breakdown, was histochemically mapped in the olfactory bulbs of 19-day-old rats. The effect of early odor experience on subsequent olfactory bulb phosphorylase activity was also examined. The highest level of phosphorylase staining in the bulb (and seemingly the highest in the brain) was in the glomerular layer, followed by the external plexiform, internal plexiform, granule cell, and olfactory nerve layers. Virtually no activity was visible in the large output neurons of the bulb, mitral, and tufted cells. Early peppermint odor experience, previously shown to increase metabolic activity in specific glomerular foci as measured by 2-deoxyglucose uptake, had no apparent effect on glomerular-layer phosphorylase activity. In some odor-familiar animals, however, patches of activity were seen in the internal plexiform layer in the area of the bulb where foci of high deoxyglucose uptake are seen in response to peppermint. The patches were directly in line with modified glomerular clusters often seen to underlie foci of enhanced deoxyglucose uptake. The existence of particularly heavy activity in the peripheral third of the glomerular layer, where glycogen-containing modified Schwann cells have been localized, raises the possibility that the glomerular-layer activity is at least partially glial in origin. Finally, because of its rich noradrenaline and serotonin innervation and high density of insulin receptors, the olfactory bulb is proposed as a model system to study the interaction of glycogen/glucose metabolism with neural activity in a relatively well-defined neuronal circuit.     

心理护理对慢性肾衰竭病人遵医行为的影响

目的：了解慢性肾衰竭病人的心理问题，观察心理护理对慢性肾衰竭病人遵医行为的影响。方法：将我科2008年1月到6月收住的80例慢性肾衰竭病人分为常规组和治方组两组，每组40人，常规组给予常规的护理措施，治疗组除常规的措施外，针对其心理问题加以指导。结果：治疗组患者焦虑等不良情绪明显低于常规组，而遵医行为优于常规组。结论：对于慢性肾衰竭患者进行有效的心理护理可以减轻其焦虑等不良情绪，提高遵医行为，控制疾病，提高生活质量。     

姜德友从肾论治痛风经验

介绍姜德友教授以肾主水液、主骨生髓理论为依据，用经验方痛风宁治疗痛风的临床经验，以期为痛风的辨证论治提供参考。     

制白附子70%乙醇提取物的完全急性毒性研究

目的：评价制白附子70%乙醇提取物的急性毒性作用。方法：灌胃给予大鼠25.0g/kg、50.0g/kg、100.0g/kg制白附子70%乙醇提取物1次,测定d1（给药当天）、d2、d3、d7、d14大鼠体重及给药前、给药后4h～28h、28～52h的饲料消耗量,计算摄食量,并于d3和d14各处死50%动物进行尸体解剖、血液生化学检查和血液细胞学检查。结果：给药第3d,低剂量组大鼠脾脏、胸腺系数增大（1.25±0.40,0.27±0.06）,高、低剂量组血清CREA含量下降（45.4±6.12μmol/L,41.7±21.4μmol/L）,高剂量组血清CK含量上升（2068.3±877.8IU/L）,以上数据与对照组比较均有统计学差异。给药14d,低、中剂量组血清CREA含量升高（70.6±15.6μmol/L,67.8±8.10μmol/L）。未观察到对大鼠体重、摄食量及血液细胞学指标有所影响。结论：制白附子70%乙醇提取物的三个受试剂量对大鼠急性毒性作用不明显。     

程子俊教授针刺治疗颈肩腰腿痛临床经验

程子俊教授以疏利经络为核心,重视奇经八脉理论的运用,善用交会穴、郄穴,坚持点-线-面-点的临床思维,临床治疗颈肩腰腿痛,疗效显著。     

张小萍治疗难治性消化性溃疡经验

介绍张小萍教授治疗难治性消化性溃疡的经验,在治疗上主张从6个方面论治:病证结合,中西合参;多方组合,配伍精当;善用对药,遣药得当;调畅气机,勿忘肝肺;久病入络,气血两调;补脾益胃,必先开胃。疗效确切。